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HCV Response Predictors

Coffee Improves Response to Hepatitis C Treatment

Drinking more coffee -- but not tea -- was associated with greater likelihood of response to hepatitis C treatment with pegylated interferon/ribavirin in the HALT-C study. alt

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Early Menopause Linked to Poor Hepatitis C Treatment Response

Women who enter menopause early have worse liver disease but are less likely to achieve sustained response to interferon-based therapy for chronic hepatitis C.

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IL28B Gene Variation Linked to Spontaneous Clearance and Treatment Response in HIV/HCV Coinfected People

A human genetic variation previously shown to predict hepatitis C prognosis in people with HCV alone may play a similar role in HIV/HCV coinfected individuals, according to a set of studies presented at the 17th Conference on Retroviruses and Opportunistic Infections (CROI 2010) last month in San Francisco. The IL28B non-risk genotype associated with both spontaneous HCV clearance and response to interferon-based hepatitis C treatment was less common among people of African descent, perhaps helping explain disparities in treatment outcomes.

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Early Menopause Linked to Poor Hepatitis C Treatment Response

Women who enter menopause early have worse liver disease but are less likely to achieve sustained response to interferon-based therapy for chronic hepatitis C.

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Older Genotype 3 Chronic Hepatitis C Patients Do Not Respond as Well to Interferon-based Therapy

Older age is associated with a lower likelihood of sustained response to pegylated interferon plus ribavirin in genotype 3 chronic hepatitis C patients, and people 50 years or older may benefit from longer treatment, according to a study presented at the recent Digestive Disease Week annual meeting (DDW 2009) in Chicago.

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