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PrEP using Tenofovir plus Emtricitabine May Offer Benefits even if HIV Infection Occurs

Animal studies of pre-exposure prophylaxis (PrEP) using tenofovir (Viread), with or without emtricitabine (Emtriva), have produced promising results, and large clinical trials in humans are currently underway. Prevention strategies using antiretroviral drugs are unlikely to be 100% effective, due to variations in efficacy, adherence, and other factors. But there is growing evidence that PrEP may have benefits even for individuals who become infected.

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How Safe is HIV Serosorting for Men who have Sex with Men?

HIV “serosorting” -- in which HIV positive people have unprotected sex only with other positive people, and negative people only with other negatives -- has been proposed as a strategy for reducing the risk of HIV transmission. The method is far from foolproof, however, requiring that individuals accurately know and honestly convey their current status.

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Agencies Release New Report on State of HIV Prevention Across the U.S.

The Kaiser Family Foundation and the National Alliance of State and Territorial AIDS Directors (NASTAD) has released a new report assessing the status of HIV prevention efforts in the U.S., at a time of increasing budget constraints.

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AIDS 2008: Protective Effect of Circumcision against HIV Infection Is Sustained for Nearly 2 Years

Over the past two years, it has become increasingly clear that adult circumcision helps protect men from acquiring HIV. As previously reported recent studies have shown that circumcision reduced the rate of HIV infection by as much as 60% in high-prevalence countries in Africa. At the XVII International AIDS Conference last week in Mexico City, researchers who conducted one of the pivotal African studies in Kisumu, Kenya, reported follow-up data showing that the benefits appear to be long-lasting.

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Antiretroviral Therapy Does Not Completely Eliminate the Risk of HIV Transmission between Heterosexual Couples

It is well known that by lowering HIV viral load in the blood and genital fluids, effective combination antiretroviral therapy can dramatically lower the risk of transmitting the virus. Some researchers, in fact, have suggested that expanded use of early therapy might significantly reduce HIV incidence on a population basis.

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