Search for Clinical Trials by State (TrialSearch@ACRIA - a national database of currently enrolling studies for HIV/AIDS and related conditions.) Open Clinical trials for HIV Infection Efficacy and Safety of Prezista/ritonavir in Treatment-experienced Patients: 24-week Results of the POWER 1 Study 2/20/07SMART Data Confirm Risk of CD4-guided Treatment Interruptions 12/08/06CD4-guided Treatment Interruptions vs Continuous Antiretroviral Therapy in Staccato Trial - 9/01/06 Reasons for Adverse SMART Outcomes Remain Poorly Understood - 8/18/06Large International Trial Finds Continuous Anti-HIV Therapy Is Greatly Superior to Treatment Interruptions: The SMART Study - 1/20/06Questions and Answers about the SMART Study - 1/20/06New Open Clinical Trials for Protease Inhibitors, Entry Inhibitors, Abacavir/Lamivudine vs Emtricitabine/Tenofovir, and Vaccine Adherence in Young IDUs - 10/31/05 Four New HIV Studies Open for Enrollment through ClinicalTrials.gov - 10/24/05
Introduction to Clinical Trials and Frequently Asked Questions
· What is a clinical trial? · Why participate in a clinical trial? · Who can participate in a clinical trial? · What happens during a clinical trial? · What is informed consent? · What are the benefits and risks of participating in a clinical trial? · What are side effects and adverse reactions? · How is the safety of the participant protected? · What should people consider before participating in a trial? · What kind of preparation should a potential participant make for the meeting with the research coordinator or doctor? · Does a participant continue to work with a primary health care provider while in a trial? · Can a participant leave a clinical trial after it has begun? · Where do the ideas for trials come from? · Who sponsors clinical trials? · What is a protocol? · What is a placebo? · What is a control or control group? · What are the different types of clinical trials? · What are the phases of clinical trials? · What is an "expanded access" protocol? · (Source: ClinicalTrials.gov)
· A - Z Dictionary
New HIV/AIDS Clinical Trials Open to Enrollment
1.
Recruiting
Pediatric Nevirapine Resistance Study Conditions: AIDS; HIV Infections
2.
Not yet recruiting
Safety of and Immune Response to an HIV Preventive Vaccine (HIV-1 gag DNA Alone or With IL-15 DNA) Given With or Without 3 Different Booster Vaccinations in HIV Uninfected Adults Condition: HIV Infections
3.
Efficacy of Tenofovir-Emtricitabine and Efavirenz in HIV Infected Patients with Tuberculosis Conditions: HIV Infections; Tuberculosis
4.
Study of the HIV gp120/NefTat/AS02A Vaccine to Treat Individuals with Chronic HIV-1 Infection on Highly Active Antiretroviral Therapy (HAART) Condition: HIV Infections
5.
Modafinil for Fatigue in HIV/AIDS Conditions: HIV Infections; Fatigue; Mental Health
6.
“OK 2004 Study” (Only Kaletra 2004 Study): Study to Evaluate Suspending Nucleosides from Triple-drug Therapy in HIV Subjects Condition: HIV Infection
7.
Safety of and Immune Response to an Experimental HIV Vaccine (VRC-HIVADV014-00-VP) in HIV Uninfected Adults Condition: HIV Infections
8.
Safety and Efficacy of an Antibody to CCR5 in Individuals with HIV who Are Not Currently on Antiretroviral Therapy Condition: HIV Infections
9.
TMC114 with Low Dose Ritonavir (RTV) and Other Antiretrovirals in Experienced HIV-1 Infected Patients with Limited or no Treatment Options Condition: HIV Infections
10.
Extended Infant Post-exposure Prophylaxis with Antiretrovirals to Reduce Postnatal HIV Transmission Condition: HIV Infections
11.
Study of the 48-Week Virologic and Immunologic Response to Lopinavir/ritonavir (Kaletra) in HIV Positive Adult Patients Condition: HIV Infections
12.
Bangkok Tenofovir Study Condition: HIV Infections
13.
Effectiveness of Nucleoside Supplementation and Substituting Tenofovir Disoproxil Fumarate for Other Drugs in Anti-HIV Regimens in Reversing Fat Loss in HIV Infected Adults Conditions: HIV Infections; Lipodystrophy; Metabolic Diseases; Nutrition Disorders
14.
The Effect of Low-dose Human Growth Hormone Therapy in HIV Infected Patients Conditions: HIV Infections; Lipodystrophy
15.
Rosuvastatin versus Pravastatin in HIV Patients Treated with Boosted Protease Inhibitors (PI) Conditions: Hyperlipidemia; HIV Infections
16.
Efavirenz or Atazanazir/Ritonavir Given with Emtricitabine/Tenofovir Disoproxil Fumarate or Abacavir/Lamivudine in HIV Infected Treatment-Naive Adults Condition: HIV Infections
17.
Observational Study of Fat Loss in HIV Infected Adults Taking Nucleoside Reverse Transcriptase Inhibitors (NRTIs) Conditions: HIV Infections; Lipodystrophy; Metabolic Diseases; Nutrition Disorders
18.
Improving HIV Screening by Nurse Rapid Testing, Streamlined Counseling Conditions: Health Care Quality, Access, and Evaluation; Delivery of Health Care; Immune System Disease; HIV Infections
FDA-Approved HIV and AIDS Treatments
Protease InhibitorsAgenerase (amprenavir) Aptivus (tipranavir)Crixivan (indinavir)Fortovase (saquinavir soft gel)Invirase (saquinavir hard gel)Kaletra (lopinavir/ritronavir)Lexiva (Fosamprenavir) Norvir (ritonavir)Prezista (darunavir)Reyataz (atazanavir) Viracept (nelfinavir)Nucleoside / Nucleotide Reverse Transcriptase InhibitorsCombivir (AZT+ 3TC)Epivir (lamivudine; 3TC)Emtriva (emtricitabine; FTC)Epzicom (abacavir + lamivudine)Hivid (zalcitabine; ddC)Retrovir (zidovudine; AZT)Trizivir (abacavir + zidovudine +lamivudine)Truvada (Tenofovir / Emtricitabine)Videx (didanosine; ddI)Viread (tenofovir)Zerit (stavudine; d4T)Ziagen (abacavir)non Nucleoside Reverse Transcriptase Inhibitors Rescriptor (delavirdine) Sustiva (efavirenz)Viramune (nevirapine)Entry Inhibitors Fuzeon (enfuvirtide; T-20)Fixed-dose CombinationsAtripla (efavirenz + emtricitabine + tenofovir) Combivir (retrovir + lamivudine)Trizivir (abacavir + zidovudine + lamivudine)Truvada (tenofovir + emtricitabine)