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• Here is a comparison chart showing the differences between
the two groups in terms of various metabolic parameters.1
• As you can see, patients in the lipodystrophy group had significant
abnormalities in two-hour glucose levels above 140 mg/dL.
• In addition, these patients were more likely than the controls
to have hypercholesterolemia and hypertriglyceridemia, as well as
reduced levels of HDL-cholesterol.
• In conclusion, patients with lipodystrophy have a metabolic
syndrome consisting of profound insulin resistance, hyperlipidemia,
and elevated cardiovascular disease risk factors.
Reference:
1. Hadigan C, Meigs JB, Corcoran C et al. Metabolic abnormalities
and cardiovascular disease risk factors in adults with human immunodeficiency
virus infection and lipodystrophy. Clin Infect Dis. 2001;32:130-9.
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