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Pegasys (peginterferon alfa-2a)

In 2005, the US Food and Drug Administration (FDA) approved PEGASYS for the treatment of chronic hepatitis B. Already the most prescribed hepatitis C medication in the United States, PEGASYS is the first and only pegylated interferon approved for the treatment of chronic hepatitis B, including both main types of the virus.

PEGASYS helps in two important ways:

- PEGASYS slows replication of the hepatitis B virus.
- PEGASYS boosts the body's immune system.

Pegasys Product Information
(Pegasys for treatment of Hepatitis B starts on page 25 of PDF)

HBV Pegasys Roche Web Page


Articles on Pegasys (peginterferon alfa-2a) for Treatment of Hepatitis B


Factors that Predict Response to Pegylated Interferon in HBeAg Positive Chronic Hepatitis B Patients
1-05-2010

Review Finds Pegylated Interferon Is More Effective than Lamivudine for Chronic Hepatitis B, but Study Shows Little Activity against HBV Genotype D
11/17/09

Early HBsAg Decline Predicts Sustained Response to Pegylated Interferon; Extended Treatment Can Improve Outcomes
11/17/09

Sustained Response in HBeAg Negative Chronic Hepatitis B Patients 3 Years After Treatment with Pegasys
8/18/09

Pegylated Interferon Monotherapy for Treatment of Chronic Hepatitis B
4/07/09

Sustained HBeAg and HBsAg Loss in Chronic Hepatitis B Patients Treated with Pegylated Interferon
9/26/08

Pegylated Interferon Alfa-2a (Pegasys) Continues to Suppress HBV, but Adding Adefovir (Hepsera) Provides No Extra Benefit in PEG for B Trial
6/03/08


Response to Pegylated Interferon in Adolescents with Chronic Hepatitis B
5/23/08

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 


Hepatitis B Main Section

FDA-approved Therapies for Chronic HBV Infection
Baraclude  (entecavir)
Epivir-HBV
  (lamivudine; 3TC)
Hepsera
  (adefovir dipivoxil)
Intron A  (interferon alfa-2b)
Pegasys  (peginterferon alfa-2a)
Viread  (tenofovir)
Tyzeka   (telbivudine)


Experimental Treatments


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