| HEPATITIS
B THERAPIES CHART | | FDA-approved
Hepatitis B Treatments |
|---|
Intron
A (interferon alfa-2b)
(Intron
A) is given by injection several times a week for six months to a year, or
sometimes longer. The drug can cause side effects such as flu-like symptoms, depression,
and headaches. Approved 1991 and available only for adults. | Pegasys
(peginterferon alfa-2a)
(Pegasys) is given by injection once a week usually for six months
to a year. The drug can cause side effects such as flu-like symptoms and depression.
Approved May 2005 and available only for adults. | Epivir-HBV
(lamivudine; 3TC)
(Epivir-HBV, Zeffix, or Heptodin)
is a pill that is taken once a day, with few side effects, for at least one year
or longer. Approved 1998 and available for both children and adults. | Hepsera
(adefovir dipivoxil)
(Hepsera)
is a pill taken once a day, with few side effects, for at least one year or longer.
Approved September 2002 for adults. Pediatric clinical trials are in progress. | Baraclude
(entecavir)
(Baraclude) is a pill taken once
a day, with few side effects, for at least one year or longer. Approved April
2005 for adults. Pediatric clinical trials are in progress. | Tyzeka
(telbivudine)
(Tyzeka,
Sebivo) is a pill taken once a day, with few side effects, for at least one year
or longer. Approved October 2006 for adults. |
Experimental
Hepatitis B Treatments | | DRUG
NAME | COMPANY | STATUS
| Emtricitabine
(FTC) | Gilead
Foster City, CA | Phase
III | Clevudine
(L-FMAU) | Pharmasset
Princeton, NJ
| Phase
III, US (2006) | Viread
(Tenofovir) | Gilead
Foster City, CA |
Approved in Europe; Phase III in US |
Valtorcitabine
(monoval
LdC) | Idenix
Cambridge, MA | Phase
II | Amdoxovir
(DAPD) | RFS
Pharm LLC
Tucker, GA | Phase
II | ANA
380
(LB80380) | Anadys
San
Diego, CA | Phase
II | Pradefovir
(Remofovir)
| Metabasis
San Diego, CA
with Valeant | Phase
II | |
| |
FDA-approved
Treatments
