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Other Infections

EACS 2015: Newest MDR-TB Drug Prices Could Fall by Up to 95% Through Generic Production

The cost of newer drugs for the treatment of multidrug-resistant tuberculosis (MDR-TB) could be cut by up to 95% if generic production of patented products could be achieved in the same way as for antiretroviral drugs, according to a study presented at the 15th European AIDS Conference last month in Barcelona. Price reductions might permit a 10-fold increase in the number of people who can be treated for MDR-TB within current budgets, without any new funding, the study suggests.

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EACS 2015: TB Death Rate 4-Fold Higher in Eastern Europe Due to Lack of Treatment after Diagnosis

People living with HIV in Eastern Europe who develop tuberculosis (TB) are 4 times more likely to die within a year when compared to similar patients in Western and Southern Europe, or Latin America, a large international study presented at the 15th European AIDS Conference last month in Barcelona has shown. The study found that even after taking into account the prevalence of resistance to first-line TB drugs and receipt of appropriate treatment, people in the other regions were around 70% less likely to die during the year following a TB diagnosis than those in Eastern Europe.

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Single Dose of Human Papillomavirus Vaccine May Prevent Most Cervical Cancer

Just 1 dose of the Cervarix human papillomavirus (HPV) vaccine was able to protect 85% of young women against cancer-causing HPV types 16 and 18, suggesting that it could prevent a majority of cervical cancer cases, including in settings were administration of the full 3-dose series is difficult, according to an analysis of data from 2 large trials published in the June 9 edition of Lancet Oncology.

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EACS 2015: 3-Month Isoniazid/Pyrazinamide Regimen Prevents TB in People with HIV

A daily 3-month regimen of isoniazid and pyrazinamide is just as effective at preventing the development of active tuberculosis (TB) in people living with HIV as a 6-month course of isoniazid alone, according to findings from a Russian study presented by Zinaida Zagdyn at the 15th European AIDS Conference last week in Barcelona.

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EASL 2015: Milk Thistle May Improve Steatohepatitis, Capsaicin from Chili Peppers Helps Fibrosis

People who used silymarin, derived from the milk thistle plant, experienced a resolution of non-alcoholic steatohepatitis (NASH) and a reduction in liver fibrosis in a randomized, placebo-controlled trial, researchers reported at the European Association for the Study of the Liver (EASL) 50th International Liver Congress last month in Vienna. Another study found that dietary capsaicin, derived from chili peppers, was associated with improvement in mice with artificially induced fibrosis, the precursor to cirrhosis.

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DHHS Proposes Rule Banning Health Service Discrimination Against Transgender People

The U.S. Department of Health and Human Services (DHHS) last week introduced a regulation that would prohibit discrimination in healthcare access and insurance coverage on the basis of sex or gender identity, including denial of services related to gender transition or reassignment. The proposal also requires healthcare providers to improve communication services for people with disabilities or limited English language proficiency.

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EASL 2015: Heavy Drinkers Contribute Most to Liver Cirrhosis Burden; Heavy Alcohol Use Rising in U.S.

The number of people who regularly consume more than a moderate amount of alcohol is a better indicator of alcoholic cirrhosis prevalence than per capita annual consumption, or the total amount consumed per year divided by the entire population, according to a presentation at the European Association for the Study of the Liver (EASL) 50th International Liver Congress last month in Vienna. A related study found that heavy drinking and binge drinking have risen over the past decade in the U.S., largely due to increases among women.

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CDC Releases Updated Sexually Transmitted Disease Treatment Guidelines

In June the U.S. Centers for Disease Control and Prevention (CDC) published updates guidelines for the treatment of sexually transmitted diseases (STDs). The guidelines include information on more than 2 dozen different sexually transmitted infections, as well as STD complications such as pelvic inflammatory disease and cervical and anal cancer.

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Coffee Helps Protect Against Liver Cancer, Obesity Confirmed as Risk Factors

Drinking coffee regularly may help prevent development of liver cancer, according to a systemic research review of 34 studies with more than 8 million total participants conducted by the World Cancer Research Fund's Continuous Update Project (CUP). The analysis also found that being overweight and heavy alcohol consumption are major risk factors for liver cancer.

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