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High Effectiveness Seen in English PrEP Trial, All Will Be Offered Truvada

An interim analysis of the English PROUD study data has shown that daily Truvada pre-exposure prophylaxis (PrEP) is highly protective against HIV for gay men and other men who have sex with men (MSM) at high risk of infection. On this basis, the PROUD Trial Steering Committee has announced that participants currently on the deferred arm of the study will be offered the opportunity to begin PrEP ahead of schedule.

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Entire Female Reproductive Tract May Be Susceptible to HIV Infection

HIV may infect T-cells throughout the female reproductive tract including the vagina, ovaries, and surrounding lymph nodes -- not only the cervix, which has been the focus of most previous research, according to a study of macaque monkeys published in the October 9 edition of PLoS Pathogens.

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More iPrEx and OLE Data Published: Adherence Higher in U.S.

Participants enrolled at the U.S. study sites of the global iPrEx trial of Truvada pre-exposure prophylaxis (PrEP) achieved better adherence than those in other countries, reaching 90% in San Francisco, researchers reported in the September 16 advance edition of Journal of Acquired Immune Deficiency Syndromes. Findings from the iPrEx open-label extension (OLE) were also recently published.

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UCSF Announces New HIV PrEP Clinic and PrEPline Phone Consultation Service

The University of California at San Francisco has opened a new clinic to help address the unmet need for Truvada pre-exposure prophylaxis, better known as PrEP. In addition, the UCSF Clinician Consultation Center at San Francisco General Hospital has received CDC funding to operate PrEPline, a telephone consultation service to provide expert guidance to healthcare providers across the nation who wish to prescribe PrEP.

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Many HIV Infections Among Gay Men May Be Related to Condom Failure

About half of all new HIV infections among men who have sex with men in Canada may occur during anal sex with a condom, suggesting that condom failure is more common than previously recognized, according to a report in the September 11 edition of PLoS ONE.

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