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NIH Halts HIV Vaccine Study Due to Lack of Effectiveness

 

The National Institutes of Institute of Allergy and Infectious Diseasesannounced this week that it will halt administration of an experimental HIV vaccine in the HVTN 505 trial, after an interim data analysis found that it neither prevented new HIV infections nor lowered viral load among people who did become infected.

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Dendritic Cell Therapeutic Vaccine Helps Immune Cells Control HIV Replication

A therapeutic vaccine made from dendritic cells primed with heat-inactivated HIV stimulated immune cells to mount a response against the virus without it infecting and killing them, according to a study described in the January 2, 2013, issue of Science Translational Medicine.

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AIDS Vaccine Conference Underway in Boston, Researchers Report Progress and Challenges

AIDS Vaccine 2012, an annual conference focusing on HIV vaccine research, takes place this week in Boston. There have been several setbacks but also some promising advances in vaccine development over the past few years, and the meeting offers an opportunity to look at where the field has been and where it is going.alt

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New Findings Help Explain Inconsistent Protection in Preventive HIV Vaccine Trial

Researchers have discovered variations in the structure of specific antibodies targeting the HIV envelope that may help explain why the ALVAC/AIDSVAX combination vaccine tested in a large trial in Thailand appeared to protect some participants but not others.

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May 18 is HIV Vaccine Awareness Day

This Friday, May 18, is HIV Vaccine Awareness Day (HVAD) in the U.S. as well as World AIDS Vaccine Day, an opportunity to raise awareness about the importance of preventive HIV vaccine research and to recognize the many study volunteers, community advocates, health professionals, and researchers who are working to find safe and effective vaccines to reduce the risk of HIV infection.alt

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