Microbicides
Microbicides
Reformulated Tenofovir Gel Found Safe and Acceptable for Anal Sex
- Details
- Category: HIV Prevention
- Published on Friday, 26 April 2013 00:00
- Written by Microbicide Trials Network
Men and women found a microbicide gel containing 1% tenofovir -- which has been shown to reduce the risk of HIV infection during vaginal sex -- to also be acceptable for anal use after it was reformulated to reduce the amount of an ingredient that led to irritation in an earlier study, according to a report in the April 3, 2013, edition of PLoS ONE.
Lubricants for Sex Can Damage Cells, but Did Not Increase HIV Risk in Lab Study
- Details
- Category: HIV Prevention
- Published on Tuesday, 11 December 2012 00:00
- Written by Liz Highleyman
Certain sexual lubricant formulations are toxic to cells and can cause damage to the epithelial lining of the vagina or rectum, but this did not appear to facilitate HIV infection, researchers reported in the November 7, 2012, edition of the open-access journal PLoS ONE. 
Vaginal Ring May Be More Effective than Gel for HIV Prevention
- Details
- Category: HIV Prevention
- Published on Tuesday, 16 October 2012 00:00
- Written by Liz Highleyman
Intravaginal rings containing the experimental NNRTIs MIV-150 or MIV-160 produced high drug concentrations in genital fluid and tissue -- higher than levels seen with vaginal gel -- and protected monkeys from infection with an HIV-like simian virus, according to a pair of recent reports from researchers at the Population Council.Other ring candidates under study deliver tenofovir and the NNRTI dapivirine.
Immune Activation Raised HIV Risk in CAPRISA Trial, but Some Develop Protective Antibodies
- Details
- Category: HIV Prevention
- Published on Tuesday, 06 November 2012 00:00
- Written by Liz Highleyman
Women in the CAPRISA 004 vaginal gel trial who showed evidence of prior immune activation had an increased likelihood of becoming infected with HIV, researchers recently reported. Another CAPRISA analysis found that 2 women exhibitedbroadly cross-neutralizing antibodies targeting a newly emergent antigen on HIV's envelope -- a discovery that could advance vaccine research.
AIDS 2012: NIH to Test Dapivirine Vaginal Ring for HIV Prevention
- Details
- Category: HIV Prevention
- Published on Friday, 03 August 2012 00:00
- Written by Press Release
A Phase 3 study will soon be underway to test a vaginal ring containing the NNRTI dapivirine (TMC120) as a potential new woman-controlled HIV prevention method, the National Institutes of Health announced at the XIX International AIDS Conference (AIDS 2012) last week in Washington, DC.
Web Design and Development by