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Treatment as Prevention/Test & Treat

ICAAC 2012: HIV May Be Shed in Semen Even If Blood Viral Load Is Undetectable

About 8% of HIV positive gay and bisexual men intermittently had detectable HIV viral load in their semen even when their blood viral load was fully suppressed, researchers reported at the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) this month in San Francisco. This is more than twice the rate seen in a similar study of heterosexual men. alt

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AIDS 2012: HPTN 052 Continues to Show Clinical Benefits of Earlier Antiretroviral Therapy

The HPTN 052 trial, best known for showing that early antiretroviral therapy (ART) can dramatically reduce the risk of HIV transmission within serodiscordant couples, also found that early treatment reduces the risk of clinical events and death, though the benefit was largely driven by extrapulmonary tuberculosis, researchers reported recently at the XIX International AIDS Conference (AIDS 2012) in Washington, DC.

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Researchers Describe Ethical Challenges of Treatment as Prevention Trial

As described in the June 2012 issue of Clinical Trials, large trials looking at HIV prevention and other public health interventions -- especially those conducted in resource-limited settings -- may face ethical issues that could affect the validity of study findings.alt

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New Guidance Addresses Expanded Antiretroviral Treatment, Perinatal ART, PrEP

On the occasion of the XIX International AIDS Conference (AIDS 2012) last week in Washington, DC, the International Antiviral Society-USA (IAS-USA) released new guidelines recommending that all people diagnosed with HIV should be offered antiretroviral therapy (ART).alt

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WHO Releases Guidelines for HIV Serodiscordant Couples

The World Health Organization (WHO) recently published a report offering guidance for serodiscordant, or mixed status, couples. WHO now recommends that HIV positive partners in such couples should received antiretroviral therapy (ART) for prevention regardless of their own CD4 T-cell count.alt

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