Back HIV-Related Conditions

HIV-Related Conditions

AIDS 2016: Managing Non-Communicable Diseases Among People Living with HIV

Speakers at the recent 21st International AIDS Conference in Durban addressed non-communicable diseases (NCDs) -- including cardiovascular diseases, diabetes, cancers, and other illnesses -- which have become more common complications for people with HIV who are living longer on antiretroviral therapy (ART). NCDs represent a significant challenge in low- and middle-income countries, where the burden of these illnesses has been reaching epidemic proportions, but where health systems have traditionally focused on providing episodic rather than chronic care.

alt

Read more:

Coverage of 21st International AIDS Conference (AIDS 2016)

HIVandHepatitis.com coverage of the 21st International AIDS Conference (AIDS 2016), held July 18-22, in Durban, South Africa.

Conference highlights include PrEP and other biomedical HIV prevention, HIV cure research, experimental antiretroviral therapy, and access to treatment and prevention for key affected populations.

Full listing by topic

AIDS 2016 website

7/28/16

alt

CROI 2016: Tenofovir HIV Treatment Raises Risk of Broken Bones

Treatment containing tenofovir is associated with a higher risk of bone fractures in people living with HIV, but a single infusion of zoledronic acid -- a drug used in the treatment of osteoporosis -- can protect against bone loss, a pair of studies presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2016) this week in Boston show.

alt

Read more:

Mild Neurological Impairment Is Common During Early HIV Infection

People with HIV infection often have neurological signs and symptoms very soon after becoming infected -- even before they develop antibodies that show up on a test -- but these are typically mild to moderate and resolve after starting effective antiretroviral therapy (ART), according to a study published in the June 10 advance online edition of Neurology. These findings provide further evidence for starting treatment as soon as possible after HIV diagnosis.

alt

Read more:

CROI 2016: Bone Density Recovers Quickly After Stopping Truvada PrEP

Bone mineral density recovers within 6 months after stopping pre-exposure prophylaxis (PrEP) containing tenofovir, Robert Grant from the University of California at San Francisco reported on behalf of the iPrEx study at Conference on Retroviruses and Opportunistic Infections (CROI 2016) this week in Boston.

alt

Read more:

CROI 2016: Antidepressant Improves HIV-Related Cognitive Impairment

The SSRI antidepressant paroxetine (Paxil) was associated with a modest improvement in cognitive function and reduced central nervous system inflammation among people with HIV-related neurocognitive disorder, but the antifungal drug fluconazole showed no apparent benefit even though it reduced oxidative stress, according to a study presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2016) last month in Boston.

alt

Read more:

Moderate Alcohol Consumption May Be More Harmful for People with HIV

People with HIV taking antiretroviral therapy (ART) had a higher likelihood of death and physiological harm at a lower level of alcohol consumption than HIV-negative individuals, according to a report published in the January 28 advance edition of Drug and Alcohol Dependence. This study "suggests the threshold for safe alcohol consumption is likely different for people with HIV," said lead author Amy Justice.

alt

Read more:

CROI 2016: Women and African Americans with HIV Have a Higher Risk of Stroke

The risk of stroke among people living with HIV is highest among people with unsuppressed viral load, and among women and African Americans, according to findings presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2016)last month in Boston.

alt

Read more:

EACS 2015: Does Low-level HIV Viral Load Raise the Risk of Disease Progression and Comorbidities?

HIV-positive people with detectable but low viral load -- in the range of 50 to 500 or 1000 copies/mL -- may continue to have a higher risk of AIDS-related events, but their likelihood of experiencing serious non-AIDS events including heart, liver, and kidney disease did not appear to increase, according to a pair of Italian studies presented at the 15th European AIDS Conference last month in Barcelona.

alt

Read more:

CROI 2016: HIV-Related Factors Increase Risk of Stroke

HIV-related risk factors seem to increase the risk of stroke -- the sudden death of brain cells due to a rupture or obstruction of blood vessels in the brain -- according to ongoing research in a growing number of large epidemiological cohort studies. Recent data from 5 of these were presented during the first-ever poster discussion session on stroke at the Conference on Retroviruses and Opportunistic Infections (CROI), which took place last month in Boston.

alt

Read more:

EACS 2015: Risk of Heart Attack Rises with Length of HIV Infection, Regardless of Age

A decade after becoming infected, a person living with HIV has approximately twice the risk of heart attack compared to someone who has just acquired HIV, regardless of the age at which they seroconverted and after taking into account the effects of aging, according to an analysis of 18,468 people with HIV presented at the 15th European AIDS Conference in Barcelona last week. Stopping smoking, improving diet, and exercising are especially important for people living with HIV long-term, the researchers suggested.

alt

Read more:

CROI 2016: Early Antiretroviral Therapy Has No Impact on Cardiovascular Disease Marker

Starting treatment at a CD4 cell count above 500 cells/mm3 does not lead to improvement in an important early warning sign of cardiovascular disease, and investigators are still unsure whether people who start treatment at high CD4 counts will have the same increased risk of cardiovascular disease as that reported in people with HIV over the past 15 years, according to findings presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2016) in Boston last week.

alt

Read more:

People with HIV Are at Higher Risk for Several Types of Cancer, Large Study Finds

People living with HIV remain at risk for AIDS-defining cancers in the era of effective antiretroviral therapy, and also have higher rates of several non-AIDS cancers than the general population, including lung, anal, and liver cancer, according to findings from a study of more than 86,000 HIV-positive people published in the October 6 Annals of Internal Medicine.

alt

Read more:

CROI 2016: Study Does Not Support Routine HPV Vaccination to Prevent Anal Cancer in People with HIV

The quadrivalent HPV vaccine Gardasil does not protect older adults with HIV against persistent anal infection with human papillomavirus or the development of high-grade anal lesions (HSIL), but the ACTG A5298 study showed some evidence that it may protect against persistent oral HPV infection, Timothy Wilkin of Weill Cornell Medical College reported at the Conference on Retroviruses and Opportunistic Infections (CROI 2016) last week in Boston.

alt

Read more:

Coverage of 2015 Interscience Conference on Antimicrobial Agents and Chemotherapy

HIVandHepatitis.com coverage of the 55th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), San Diego, September 17-21, 2015.

Highlights of this year's conference include experimental antiretroviral drugs and treatment strategies, HIV prevention, and comorbidities among people with HIV and HIV/HCV coinfection.

Full listing by topic

ICAAC website

10/6/15

alt

CROI 2016: Early Antiretroviral Therapy Reduces the Risk of Infection-Related Cancers

People who started antiretroviral therapy at a CD4 cell count above 500 had a significantly lower risk of developing a cancer with an infectious cause when compared to people who started treatment at a CD4 count of 350 or below, an analysis of the START study presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2016) in Boston has shown.

alt

Read more:

IAS 2015: Bone Loss Slows, but Continues Long-term in HIV-positive People on Antiretroviral Therapy

People with HIV experienced a decrease in bone density at the hip and spine during their first 2 years after starting antiretroviral therapy (ART). While bone loss slowed after 96 weeks, it continued to decline more rapidly among HIV-positive people compared with the usual age-related bone loss seen in HIV-negative people over 7 years, researchers reported at the recent 8th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention in Vancouver.

alt

Read more:

Coverage of the 2016 Conference on Retroviruses and Opportunistic Infections

HIVandHepatitis.com coverage of the 2016 Conference on Retroviruses and Opportunistic infections (CROI 2016), February 22-25, 2016, in Boston.

Conference highlights include PrEP and other HIV prevention innovations, new HIV treatment strategies, HIV cure research, the cascade of care, HIV-related conditions, and optimizing therapy for hepatitis C.

HIVandHepatitis.com coverage by topic

CROI website

2/26/16

alt

IAS 2015: HIV+ People with Asymptomatic Cognitive Impairment More Likely to Develop Symptoms

People with HIV who showed evidence of asymptomatic neurocognitive impairment at study entry were nearly twice as likely to progress to symptomatic HIV-associated neurocognitive disorders than those with initially normal neuropsychological tests, according to research presented at the 8th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention last month in Vancouver.

alt

Read more:

CROI 2016: HIV in the Brain -- New Tools and Treatment Options to Keep Your Mind Beautiful

In the future, HIV-related neurocognitive disorder (HAND) may become less common because of the earlier use of antiretroviral therapy (ART), but neurological disease -- caused by a number of different factors -- will remain an important issue as people with HIV live longer, according to several presentations in a symposium called "A beautiful Mind, Keeping It," held at the annual Conference on Retroviruses and Opportunistic Infections (CROI 2016) in Boston.

alt

Read more:

IAS 2015: International AIDS Society Conference Starts this Weekend in Vancouver

The 8th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2015) starts this Sunday and runs July 19-22 in Vancouver. HIV prevention -- including treatment-as-prevention and pre-exposure prophylaxis (PrEP) -- will be a major focus of the meeting. Other topics will include antiretroviral drugs in development, expanding access to treatment and retention in care, and HIV/hepatitis coinfection. HIVandHepatitis.com will be on site covering the latest news.

alt

Read more: