AIDS 2014: Romidepsin Activates Latent HIV, But Does Not Decrease Viral Reservoir

The HDAC inhibitor romidepsin was able to awaken latent HIV in resting T-cells, causing it to start producing new virus, but this was not associated with a decrease in the size of the viral reservoir in T-cells, researchers reported at the 20th International AIDS Conference this week in Melbourne. This finding suggests that kicking HIV out of hiding will not be adequate for a functional cure without strengthening immune response against the virus.


AIDS 2014: Positively Fabulous Aims to Change HIV+ Women's Lives [VIDEO]

The Positively Fabulous campaign -- participants in the Global Village at the 20th International AIDS Conference taking place this week in Melbourne, Australia --  uses art to empower women living with HIV and helps them set the agenda for responding to the epidemic.


AIDS 2014: Researchers Discuss Progress Towards an HIV Cure [VIDEO]

Progress along the multi-pronged path towards a cure for HIV was one of the themes at the 20th International AIDS Conference (AIDS 2014), taking place this week in Melbourne. Researchers provided updates on the "Mississippi Baby," a novel assay for detecting low levels of hidden virus in the body, and using the anti-cancer drug romidepsin to reactivate latent virus.


AIDS 2014: Law and Policy Must Be Part of the Solution for AIDS [VIDEO]

Reforming laws that criminalize and discriminate against people with HIV and key affected populations is a necessary part of the response to the epidemic, according to renowned Australian jurist the Hon. Michael Kirby, speaking at the 20th International AIDS Conference (AIDS 2014) taking place this week in Melbourne, Australia.


AIDS 2014: No One Left Behind in Response to HIV/AIDS [VIDEO]

The global response to HIV/AIDS has made some remarkable progress since the last such gathering in 2012, but more remains to be done to ensure that no one is left behind, UNAIDS Executive Direct Michel Sidibé said on the opening day of the 20th International AIDS Conference (AIDS 2014), taking place this week in Melbourne, Australia.


Michel Sidibé speaks at AIDS 2014 opening press briefing, July 20, 2014

"More has been done in last 3 years than in the last 25 years," Sidibé said. "We quickened the pace, and we changed completely the trajectory of the response."

But we face a new generation of challenges, he added. "Because of stigma, discrimination, because of exclusion, because of criminal laws, people are hiding themselves and people are afraid to use services." It is estimated that only about half of people living with HIV worldwide know their status, and 75% of new infections and deaths due to AIDS are concentrated in 15 countries.



M Sidibé.Justice For All: Ending AIDS Means Leaving No One Behind. 20th International AIDS Conference (AIDS 2014). Melbourne, July 20-25, 2014. Opening session and press briefing.

TAG Releases 2014 HIV, Hepatitis C, and Tuberculosis Pipeline Report

The Treatment Action Group (TAG) and HIV i-Base this week released the latest edition of their annual Pipeline Report, covering new therapies and related technologies for HIV, hepatitis C, and tuberculosis (TB), in conjunction with the 20th International AIDS Conference taking place this week in Melbourne, Australia.


AIDS 2014: International AIDS Conference Open with Tributes and Determination

The 20th International AIDS Conference (AIDS 2014) kicked off Sunday in Melbourne, Australia. With the theme of "Stepping Up the Pace" in the response to HIV/AIDS, delegates will focus on expanded access to HIV and hepatitis C treatment, the promise of biomedical prevention, ending criminalization of people with HIV, and reaching key populations including gay men, transgender people, sex workers, prisoners, and people who use drugs.