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Coverage of HIV Research for Prevention Conference (HIVR4P 2016)

HIVandHepatitis.com coverage of the 2016 HIV Research for Prevention Conference (HIVR4P 2016), October 17-21, in Chicago.

Conference highlights include current and experimental pre-exposure prophylaxis (PrEP), microbicide rings and other options, and investigational HIV vaccines.

Full listing of coverage by topic

HIVR4P 2016 website

10/22/16

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HIVR4P 2016: Vaginal and Rectal Bacteria May Influence HIV Transmission and Microbicide Efficacy

A number of presentations at the HIV Research for Prevention Conference (HIVR4P 2016) this week in Chicago looked at the influence of vaginal bacteria on HIV susceptibility, with one study finding that vaginal bacteria may have profound effects on levels of certain drugs used as microbicides -- but not others. A poster at the conference also looked at bacteria in the rectum in gay men, finding a correlation between condomless anal sex and changes in the predominant bacterial species which may similarly increase susceptibility to HIV infection.

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HIVR4P 2016: Second Case Report of PrEP Failure Due to Drug-Resistant Virus

A PrEP user in New York City has become HIV-positive with virus that is resistant to Truvada and other antiretroviral drugs, according to a report presented Tuesday at the HIV Research for Prevention (HIVR4P 2016) conference in Chicago. This is only the second such case that has been reported, highlighting the rarity -- but not the impossibility -- of HIV infections among people who adhere to their pre-exposure prophylaxis (PrEP) medication schedule.

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HIVR4P 2016: Policymakers' Inaction is Leading People to Take "PrEP in the Wild"

An increasing number of gay men and others at risk for HIV are seeking to protect their health with pre-exposure prophylaxis (PrEP), but the lack of PrEP provision and regulatory approval in many countries is leading people to take it without medical supervision and on an ad-hoc basis. This will undermine the safety and effectiveness of PrEP, said Jerome Galea as he presented results of the PrEP in the Wild survey at the HIV Research for Prevention conference (HIVR4P 2016) this week in Chicago.

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HIVR4P 2016: Anal Sex May Transmit 4 in 10 HIV Infections Among High-Risk U.S. Women

A study presented at the HIV Research for Prevention conference this week in Chicago suggests that among women at high risk for HIV infection, 40% or more infections might be transmitted via anal intercourse. Because HIV is transmitted, according to different estimates, from 2 to 18 times more easily via anal than vaginal sex (the Centers for Disease Control and Prevention's estimate is 12 times), anal intercourse could be a major -- or even predominant -- contributor to HIV infections in heterosexual women, even if anal sex accounts for only 5%-10% of all sex.

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