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HIVR4P 2016: Policymakers' Inaction is Leading People to Take "PrEP in the Wild"

An increasing number of gay men and others at risk for HIV are seeking to protect their health with pre-exposure prophylaxis (PrEP), but the lack of PrEP provision and regulatory approval in many countries is leading people to take it without medical supervision and on an ad-hoc basis. This will undermine the safety and effectiveness of PrEP, said Jerome Galea as he presented results of the PrEP in the Wild survey at the HIV Research for Prevention conference (HIVR4P 2016) this week in Chicago.

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HIVR4P 2016: Second Case Report of PrEP Failure Due to Drug-Resistant Virus

A PrEP user in New York City has become HIV-positive with virus that is resistant to Truvada and other antiretroviral drugs, according to a report presented Tuesday at the HIV Research for Prevention (HIVR4P 2016) conference in Chicago. This is only the second such case that has been reported, highlighting the rarity -- but not the impossibility -- of HIV infections among people who adhere to their pre-exposure prophylaxis (PrEP) medication schedule.

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Truvada PrEP Linked to Rare Case of Serious Kidney Disorder

Researchers in Southern California have identified the first known case of Fanconi syndrome, a type of serious kidney dysfunction, in an otherwise healthy man taking Truvada (tenofovir/emtricitabine) for pre-exposure prophylaxis (PrEP), according to a poster presented at the 18th International Workshop on Co-morbidities and Adverse Drug Reactions in HIV last month in New York City. This case underlines the importance of regular kidney function monitoring while on PrEP.

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HIVR4P 2016: Anal Sex May Transmit 4 in 10 HIV Infections Among High-Risk U.S. Women

A study presented at the HIV Research for Prevention conference this week in Chicago suggests that among women at high risk for HIV infection, 40% or more infections might be transmitted via anal intercourse. Because HIV is transmitted, according to different estimates, from 2 to 18 times more easily via anal than vaginal sex (the Centers for Disease Control and Prevention's estimate is 12 times), anal intercourse could be a major -- or even predominant -- contributor to HIV infections in heterosexual women, even if anal sex accounts for only 5%-10% of all sex.

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AIDS 2016: How Can Clinical Services Engage Men Who Have Sex With Men in Africa?

Men who have sex with men (MSM) living in African countries have an extremely high burden of HIV, Stefan Baral of Johns Hopkins University reminded delegates at the recent 21st International AIDS Conference (AIDS 2016) in Durban. But in situations often marked by widespread social disapproval of homosexual behavior, health services for MSM are few and far between.

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