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HCV Sexual Transmission

Little Overlap of Sexually Transmitted HCV between U.S. and Europe

A phylogenetic analysis of more 200 hepatitis C virus (HCV) strains from HIV positive gay and bisexual men revealed extensive clustering of related viruses within U.S. cities, but little overlap between the East and West coasts, or between the U.S. and Europe or Australia, according to findings presented at the at the 18th Conference on Retroviruses and Opportunistic Infection (CROI 2011) this month in Boston.

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Sexual Transmission of Hepatitis C among HIV Positive Men in the U.S. and Australia

Nearly three-quarters of new hepatitis C virus (HCV) infections among HIV positive gay and bisexual men in the U.S. are likely due to sexual transmission, according to an analysis described in the January 31, 2011 advance online issue of Clinical Infectious Diseases. An Australian study published in the same issue found that sexual transmission accounted for a majority of cases among men who have sex with men, but injection drug use also played a role. These findings suggest that HIV positive people who have risky sex should undergo regular hepatitis C testing.

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Acute Hepatitis C as a Sexually Transmitted Infection in HIV Positive Men

Sexual transmission of hepatitis C virus (HCV) among HIV positive men who have sex with men has now been recognized for a decade, occurring in cities in Europe, North America, and Australia. Since acute HCV outbreaks occur almost exclusively among men with HIV, being HIV positive probably plays a critical role, according to the authors of a review article in the July 31, 2010 issue of AIDS.

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Danish Study Looks at Hepatitis C Sexual Transmission among HIV Positive Gay Men

Less than 1% of HIV positive gay and bisexual men seen at a Danish hospital were found to have acute hepatitis C virus (HCV) infection, according to a study presented at the American Association for the Study of Liver Diseases "Liver Meeting" (AASLD 2010) this week in Boston. All those who started hepatitis C treatment within 6 months of becoming infected achieved rapid virological response, while 1 who started later experienced HCV relapse.

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Reappearance of HCV in Gay Men Is Usually Due to Re-infection, Not Late Relapse

Re-emergence of hepatitis C virus (HCV) in gay and bisexual men who were previously treated and achieved sustained virological response with interferon-based therapy appears to be due to reinfection, not late relapse occurring after the usual window for determining a cure, according to a genetic sequencing study described in the April 1, 2010 Journal of Acquired Immune Deficiency Syndromes.

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