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Hepatitis C

Low-density Lipoprotein Receptor Plays a Role in HCV Infection of Liver Cells

Past research has suggested that the low-density lipoprotein (LDL) cholesterol receptor plays a role in hepatitis C virus (HCV) infection, but the process is not well understood. As reported in the March 2007 Journal of Hepatology, in a laboratory study French researchers assessed expression and activity of the LDL receptor in the absence or presence of squalestatin (which up-regulates LDL receptor expression) or 25-hydroxycholesterol (which down-regulates LDL receptor expression).

More Evidence that Hepatitis C Virus Infection is Associated with Insulin Resistance

Research to date has produced conflicting data about the relationship between hepatitis C virus (HCV) infection and insulin resistance.

African Americans with Genotype 1 Hepatitis C Less Likely to Have Steatosis

The aim of the present study, published in the January 2007 issue of Hepatology, was to compare rates of hepatic steatosis in African American and Caucasian American patients with chronic genotype 1 hepatitis C who participated in a prospective clinical trial of pegylated interferon plus ribavirin.