51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)ICAAC 2011: New Integrase Inhibitor BI 224436 Active against Raltegravir-Resistant HIV
- Details
- Category: HIV Treatment
- Published on Friday, 07 October 2011 00:00
- Written by Liz Highleyman
Boehringer Ingelheim's novel integrase inhibitor candidate BI 2244336, which works by a different mechanism than existing drugs in its class, demonstrated potent antiviral activity and a good pharmacokinetic profile in a series of early studies presented at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2011) last month in Chicago.
ICAAC 2011: Declining Prevalence of HIV Triple-class and Protease Inhibitor Resistance
- Details
- Category: HIV Treatment
- Published on Friday, 07 October 2011 00:00
- Written by Liz Highleyman
HIV strains showing resistance to protease inhibitors, or to all 3 of the earliest classes of antiretroviral drugs, have become less common over the past several years, making it easier to construct effective regimens, researchers reported at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2011) last month in Chicago.
ICAAC 2011: Monoclonal Antibody Ibalizumab May Hold Promise for Treatment-Experienced HIV Patients
- Details
- Category: HIV Treatment
- Published on Tuesday, 04 October 2011 00:00
- Written by Liz Highleyman
Ibalizumab (also known as TMB-355, formerly TNX-355) -- an antibody-based therapy for HIV -- was well-tolerated and significantly reduced viral load over 24 weeks when used with optimized background therapy, researchers reported at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2011) last month in Chicago.
ICAAC 2011: Double Dose of Hepislav Works as Well as 3 Doses of Standard HBV Vaccine
- Details
- Category: HBV Prevention
- Published on Friday, 07 October 2011 00:00
- Written by Dynavax
Two injections of Dynavax's investigational Heplisav hepatitis B virus (HBV) vaccine protected adults over age 40 as well as the standard regimen consisting of 3 doses of the Engerix-B vaccine given over 6 months, researchers reported at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2011) last month in Chicago.
ICAAC 2011: HPV Testing and Pap Smears Identify Anal Cancer Risk in HIV+ Men
- Details
- Category: Human Papillomavirus (HPV)
- Published on Friday, 30 September 2011 00:00
- Written by Liz Highleyman
Human papillomavirus (HPV) testing and anal Pap testing can detect abnormal cell changes that could progress to anal cancer in HIV positive gay men at an earlier and more treatable stage, and is likely to be cost-effective, according to a study presented at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2011) this month in Chicago.
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- ICAAC 2011: Omitting Inactive NRTIs from Salvage Regimen Can Maintain Viral Suppression
- ICAAC 2011: Maraviroc May Reduce Liver Fibrosis in HIV/HCV Coinfected People
- ICAAC 2011: Lopinavir/ritonavir Reduces Mother-to-Child HIV Transmission during Supplemental Breastfeeding
- ICAAC 2011: Cobicistat Matches Ritonavir as Booster, Studies Clarify Effects on Kidney Function
- ICAAC 2011: Zinc Finger Gene Therapy Boosts CD4 Cells, May Lower HIV Viral Load
- ICAAC 2011: Raltegravir is Effective and Well-tolerated in Diverse Populations with HIV
- ICAAC 2011: Didanosine, Higher HCV Viral Load Predict Liver Fibrosis in HIV/HCV Coinfected People
- ICAAC 2011: BMS-790052 plus Standard Therapy Cures Most Genotype 1 Hepatitis C Patients
- ICAAC 2011: HCV Drug Telaprevir Shows No Problematic Interactions with Raltegravir
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