Discovery May Aid Development of Hepatitis C Vaccine
- Details
- Category: HCV Vaccines
- Published on Thursday, 15 September 2011 00:00
- Written by University of New South Wales
Australian researchers have shed new light on the natural history of hepatitis C virus (HCV) by performing a longitudinal genetic analysis of the virus in 4 patients from the first few weeks after infection until resolution (spontaneous clearance or establishment of chronic infection).
Experimental HCV Vaccine Induces Broadly Neutralizing Antibodies in Mice and Monkeys
- Details
- Category: HCV Vaccines
- Published on Friday, 05 August 2011 00:00
- Written by Liz Highleyman
French researchers have taken a further step toward the elusive goal of a vaccine for hepatitis C, using virus-like particles that stimulate a broad neutralizing antibody response effective against multiple HCV genotypes, according to a report in the August 3, 2011, issue of Science Translational Medicine. 
Little Overlap of Sexually Transmitted HCV between U.S. and Europe
- Details
- Category: HCV Sexual Transmission
- Published on Tuesday, 15 March 2011 01:38
- Written by Liz Highleyman
A phylogenetic analysis of more 200 hepatitis C virus (HCV) strains from HIV positive gay and bisexual men revealed extensive clustering of related viruses within U.S. cities, but little overlap between the East and West coasts, or between the U.S. and Europe or Australia, according to findings presented at the at the 18th Conference on Retroviruses and Opportunistic Infection (CROI 2011) this month in Boston.
New Phase 2b Study of Experimental Hepatitis C Vaccine ChronVac-C
- Details
- Category: HCV Vaccines
- Published on Friday, 18 March 2011 00:54
- Written by Inovio
Inovio Pharmaceuticals this week announced that its partner ChronTech has started a new Phase 2 clinical trial to evaluate an investigational therapeutic hepatitis C virus (HCV) vaccine candidate known as ChronVac-C. In early studies the vaccine increased T-cell responses against HCV, suppressed viral load, and appeared to be safe and well-tolerated.
Sexual Transmission of Hepatitis C among HIV Positive Men in the U.S. and Australia
- Details
- Category: HCV Sexual Transmission
- Published on Friday, 25 February 2011 03:56
- Written by Liz Highleyman
Nearly three-quarters of new hepatitis C virus (HCV) infections among HIV positive gay and bisexual men in the U.S. are likely due to sexual transmission, according to an analysis described in the January 31, 2011 advance online issue of Clinical Infectious Diseases. An Australian study published in the same issue found that sexual transmission accounted for a majority of cases among men who have sex with men, but injection drug use also played a role. These findings suggest that HIV positive people who have risky sex should undergo regular hepatitis C testing.
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