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Danish Study Looks at Hepatitis C Sexual Transmission among HIV Positive Gay Men

Less than 1% of HIV positive gay and bisexual men seen at a Danish hospital were found to have acute hepatitis C virus (HCV) infection, according to a study presented at the American Association for the Study of Liver Diseases "Liver Meeting" (AASLD 2010) this week in Boston. All those who started hepatitis C treatment within 6 months of becoming infected achieved rapid virological response, while 1 who started later experienced HCV relapse.

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Acute Hepatitis C as a Sexually Transmitted Infection in HIV Positive Men

Sexual transmission of hepatitis C virus (HCV) among HIV positive men who have sex with men has now been recognized for a decade, occurring in cities in Europe, North America, and Australia. Since acute HCV outbreaks occur almost exclusively among men with HIV, being HIV positive probably plays a critical role, according to the authors of a review article in the July 31, 2010 issue of AIDS.

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Hepatitis C Remains Uncommon Among HIV Negative Gay Men

Hepatitis C virus (HCV) infection was uncommon, with a prevalence less than 1%, among more than 2000 gay and bisexual men screened at sexual health clinics in the U.K., according to a study reported in the May 2010 Journal of Infection. This is close to the rate of the general population in England, suggesting that recent outbreaks of acute hepatitis C among men who have sex with men is limited to those with HIV.

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Reappearance of HCV in Gay Men Is Usually Due to Re-infection, Not Late Relapse

Re-emergence of hepatitis C virus (HCV) in gay and bisexual men who were previously treated and achieved sustained virological response with interferon-based therapy appears to be due to reinfection, not late relapse occurring after the usual window for determining a cure, according to a genetic sequencing study described in the April 1, 2010 Journal of Acquired Immune Deficiency Syndromes.

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CROI 2010: Hepatitis C Virus Can Survive in Syringes Up to 2 Months under Favorable Conditions

Hepatitis C virus (HCV) can survive under certain conditions for prolonged periods in syringes used to inject drugs, thereby increasing the potential for HCV transmission, researchers reported at the 17th Conference on Retroviruses and Opportunistic Infections (CROI 2010) last week in San Francisco. These findings are important for shaping needle exchange policies and practices.

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