TB Fixed-dose Coformulation Works as Well as Separate Drugs

A 4-drug combination containing rifampicin, isoniazid, pyrazinamide, and ethambutol treats pulmonary tuberculosis (TB) as effectively as individual medications.

CROI 2011: Immediate ART Improves Survival for HIV+ People with TB

Tuberculosis patients who immediately start antiretroviral therapy are less likely to progress to AIDS or die, but among people with higher CD4 counts, waiting reduces the risk of IRIS, researchers reported at CROI 2011. alt

New Vaccine May Be More Effective against Tuberculosis

A new vaccine known as H56 promotes CD4 T-cell response and may be more effective in preventing tuberculosis than the widely used BCG vaccine, according to results from an international study published in the February 2011 issue of Nature Medicine. Experiments in mice showed that H56 vaccination conferred protective immunity and, if given after exposure to Mycobacterium tuberculosis, lowered the amount of bacteria and suppressed its reactivation.

March 24 is World TB Day

Thursday, March 24, is designated as World TB Day, calling attention to a disease that is a major killer worldwide, especially of people with HIV/AIDS.

Tuberculosis Coinfection Increases Risk of Mother-to-Child HIV Transmission

HIV positive women coinfected with tuberculosis (TB) are more likely to transmit HIV to their babies during pregnancy, according to a study described in the February 1, 2011, Journal of Infectious Diseases. These findings underline the importance of TB treatment and use of antiretroviral therapy (ART) to prevent HIV transmission.