- Category: HIV Testing & Diagnosis
- Published on Thursday, 23 July 2015 00:00
- Written by Roger Pebody
In addition to recommending that routine HIV testing in medical settings be expanded to reach new groups, the World Health Organization’s new guidance on HIV testing also recommends the delivery of testing by non-medical 'lay providers," often in community settings. The guidance urges planners to make careful, strategic choices about which HIV testing interventions will be best able to reach individuals with undiagnosed HIV. New approaches may be needed to reach key populations.
Self-testing is not yet recommended. This is because the evidence base for its effectiveness and the best ways to provide it is still emerging. But the substantial time that the WHO gave to discussing self-testing when launching their guidance at the 8th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention this week in Vancouver suggests that the approach will have an important place in future guidelines.
Improvements in HIV testing services are needed if the global targets of 90-90-90 are to be achieved. But many countries are lagging further behind on the objective of diagnosing 90% of people living with HIV than on the other 2 targets.
"The first 90 -- diagnosis of HIV -- is essential to the second 90 -- initiation of ART among people with HIV -- and the ultimate outcome of the third 90 -- viral load suppression among people on ART," the guidance says.
Due to HIV testing’s role in the treatment cascade, linkage to care is seen as an essential component of HIV testing services. Suggested practices include offering immediate antiretroviral therapy to people testing at home, integration of HIV testing and treatment services, transportation vouchers, support from peers or lay providers, and case-management approaches. Moreover, people receiving an HIV-negative result may need linkage to HIV prevention services.
Counseling is still seen as a key component, but providers need to do more than counsel and test. Hence the shift in terminology from voluntary testing and counseling (VTC) and HIV testing and counseling (HTC) to the current preferred term: HIV testing services (HTS).
For the first time, WHO recommends a larger role for lay providers in HIV testing. Lay providers are people who have been trained to deliver specific health services but do not have a formal medical education. This is in part a response to workforce and financial shortages. But it also allows HIV testing services to be provided differently, by people who are peers of those getting tested. They may be able to offer culturally competent, non-judgmental and respectful support which can improve the uptake of HIV testing in key populations such as men who have sex with men, sex workers, and people who inject drugs.
The guidelines recommend that lay providers be carefully selected, trained, and appropriately remunerated. Many countries will need to adjust their national policies to allow lay providers to be involved in all stages of HIV testing, including collecting the specimens and delivering the results.
The guidance reviews a range of ways of providing HIV testing. This includes testing in health facilities (standalone VCT or provider-initiated testing when the client is seeking healthcare for another reason), as well as a range of community-based HIV testing services (including outreach, door to door testing in homes, national campaigns, multi-disease campaigns, and workplace testing). WHO coins a new term -- "test for triage" -- to describe community-testing services which will systematically refer people to other services for confirmation of what appear to be HIV-positive results.
Selecting the most appropriate interventions requires careful assessment of the prevalence of HIV in different social groups, current uptake of HIV testing services, the available resources, cost-effectiveness, and the preferences of people needing testing.
Rachel Baggaley of WHO noted that there is frequently a mismatch between the populations served by existing testing services and the populations with undiagnosed HIV. Due to the success of integrating HIV testing into antenatal and reproductive health services, in every region of the world a majority of those taking an HIV test are women. However in every region apart from Africa, a majority of those testing positive are men.
She re-iterated that the objective of HIV testing services is to identify and test people who are unaware of their HIV infection, and to do so as early in the course of their infection as possible. The HIV testing approaches that should be selected must be those which result in the highest proportion of HIV-positive diagnoses in priority populations.
For example, outreach to key populations may raise testing rates in people who feel excluded from mainstream health services. Programs which encourage the sexual partners of pregnant women to come in for testing may help raise testing rates in men. Routine testing in health facilities can reach substantial numbers of people at a low cost and is appropriate where the prevalence of undiagnosed HIV remains high.
Cheryl Johnson of WHO outlined the emerging evidence on self-testing (home testing), but said that the public health response is lagging behind public demand. HIV tests designed for self-testing are already legal and commercially available in several countries, while HIV tests intended for use by health professionals are already being used by individuals in an unregulated way elsewhere. The most appropriate ways to deliver and distribute self-testing kits have not yet been defined.
"Expanding testing is probably the single most powerful game changer," said Luiz Loures, deputy executive director of UNAIDS. "Self-testing is the fundamental direction that we should take -- knowing your status is a fundamental right. We need to find a way to bring testing closer to the people who are discriminated against by health systems."
World Health Organization. Consolidated guidelines on HIV testing services, 2015.
R. Baggaley. Launch of the WHO Consolidated HIV testing services guidelines: Overview of the guidelines. 8th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention. Vancouver, July 19-22, 2015.Presentation SUSA0602.
C Johnson. Overview of the evidence and experience with HIV self-testing (HIVST). 8th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention. Vancouver, July 19-22, 2015. Presentation. SUSA0603.