Back HIV Prevention Pre-exposure (PrEP) IAS 2015: PrEP Adherence, Sexual Behavior, and HIV and STI Incidence [VIDEO]

IAS 2015: PrEP Adherence, Sexual Behavior, and HIV and STI Incidence [VIDEO]

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An open-label Truvada pre-exposure prophylaxis (PrEP) demonstration project, which included more than 500 mostly gay and bisexual men in San Francisco, Miami, and Washington, DC, showed that adherence was generally good overall -- especially among people at highest risk for HIV infection -- but there were some important disparities, researchers reported at the recent 8th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention in Vancouver.

Albert Liu from the San Francisco Department of Public Health gave an overview of the Demo Project findings at an IAS media briefing on PrEP implementation.

[Albert Liu, IAS 2015, July 20, 2015]

More than a quarter of participants had sexually transmitted infections at baseline, but this did not increase after starting once-daily Truvada (tenofovir/emtricitabine) PrEP, Liu said. There were 2 new HIV infections during follow-up, but both occurred in people with low or undetectable tenofovir levels at time of seroconversion.

"Our results support strongly the scale-up of PrEP in these clinical settings," Liu concluded. "Our findings highlight the need for strategies to address racial and geographical disparities as well as housing instability to maximize the impact of PrEP."

SEE ALSO: 

IAS 2015: U.S. PrEP Demo Project Finds People at Highest HIV Risk Take PrEP Most Consistently

9/2/15

References

8th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention. PrEP Implementation media briefing, July 20, 2015.

A Liu, S Cohen, E Vittinghoff, et al. Adherence, sexual behavior and HIV/STI incidence among men who have sex with men (MSM) and transgender women (TGW) in the US PrEP demonstration (Demo) project. 8th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention. Vancouver, July 19-22, 2015. AbstractTUAC0202.